Tumor volume growth delay studies. Immunocompromised NOD/SCID or Nude mice receive cell line-matrigel mixture injection (subcutaneous).
The patient derived xenografts combine the advantages of working with the cancer cells harvested from a patient with the physiological relevance of an in vivo host.
Evaluate the efficacy of a panel of chemotherapy drugs for individual donor. Develop new therapeutic agents optimized for individual donor.